Cargando…

Characterization of H type 1 and type 1 N-acetyllactosamine glycan epitopes on ovarian cancer specifically recognized by the anti-glycan monoclonal antibody mAb-A4

Cancer-specific glycans of ovarian cancer are promising epitopes for targeting with monoclonal antibodies (mAb). Despite their potential, structural characterization of these glycan epitopes remains a significant challenge in mAb preclinical development. Our group generated the monoclonal antibody m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choo, Matthew, Tan, Heng Liang, Ding, Vanessa, Castangia, Roberto, Belgacem, Omar, Liau, Brian, Hartley-Tassell, Lauren, Haslam, Stuart M., Dell, Anne, Choo, Andre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391748/ https://www.ncbi.nlm.nih.gov/pubmed/28167527 http://dx.doi.org/10.1074/jbc.M116.768887

Ejemplares similares

Effects of altered sialic acid biosynthesis on N-linked glycan branching and cell surface interactions
por: Pham, Nam D., et al.
Publicado: (2017)

Glycan Analysis and Influenza A Virus Infection of Primary Swine Respiratory Epithelial Cells: THE IMPORTANCE OF NeuAcα2–6 GLYCANS
por: Bateman, Allen C., et al.
Publicado: (2010)

The Type B Flagellin of Hypervirulent Clostridium difficile Is Modified with Novel Sulfonated Peptidylamido-glycans
por: Bouché, Laura, et al.
Publicado: (2016)

Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation
por: Barthel, Steven R., et al.
Publicado: (2011)

Common Polymorphisms in Human Langerin Change Specificity for Glycan Ligands
por: Feinberg, Hadar, et al.
Publicado: (2013)

Glycomics Profiling of Chinese Hamster Ovary Cell Glycosylation Mutants Reveals N-Glycans of a Novel Size and Complexity
por: North, Simon J., et al.
Publicado: (2010)

A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2
por: Jégouzo, Sabine A. F., et al.
Publicado: (2015)

Prolectin, a Glycan-binding Receptor on Dividing B Cells in Germinal Centers
por: Graham, Sarah A., et al.
Publicado: (2009)

β-N-Acetylhexosaminidases HEXO1 and HEXO3 Are Responsible for the Formation of Paucimannosidic N-Glycans in Arabidopsis thaliana
por: Liebminger, Eva, et al.
Publicado: (2011)

Significant Impact of Single N-Glycan Residues on the Biological Activity of Fc-based Antibody-like Fragments
por: Jez, Jakub, et al.
Publicado: (2012)

Identification of multiple isomeric core chitobiose–modified high-mannose and paucimannose N-glycans in the planarian Schmidtea mediterranea
por: Subramanian, Sabarinath Peruvemba, et al.
Publicado: (2018)

Distinct Fcα receptor N-glycans modulate the binding affinity to immunoglobulin A (IgA) antibodies
por: Göritzer, Kathrin, et al.
Publicado: (2019)

High Throughput Screening for Compounds That Alter Muscle Cell Glycosylation Identifies New Role for N-Glycans in Regulating Sarcolemmal Protein Abundance and Laminin Binding
por: Cabrera, Paula V., et al.
Publicado: (2012)

Identification of Mono- and Disulfated N-Acetyl-lactosaminyl Oligosaccharide Structures as Epitopes Specifically Recognized by Humanized Monoclonal Antibody HMOCC-1 Raised against Ovarian Cancer
por: Shibata, Toshiaki K., et al.
Publicado: (2012)

Identification of Neutrophil Granule Glycoproteins as Lewis(x)-containing Ligands Cleared by the Scavenger Receptor C-type Lectin
por: Graham, Sarah A., et al.
Publicado: (2011)

Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells
por: Wittmann, Alexandra, et al.
Publicado: (2016)

Structure of a Complex Phosphoglycan Epitope from gp72 of Trypanosoma cruzi
por: Allen, Simon, et al.
Publicado: (2013)

Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes
por: Nonaka, Motohiro, et al.
Publicado: (2014)

Glycosylation Patterns of HIV-1 gp120 Depend on the Type of Expressing Cells and Affect Antibody Recognition
por: Raska, Milan, et al.
Publicado: (2010)

Engineering of Sialylated Mucin-type O-Glycosylation in Plants
por: Castilho, Alexandra, et al.
Publicado: (2012)

A Mucin-type O-Glycosyltransferase Modulates Cell Adhesion during Drosophila Development
por: Zhang, Liping, et al.
Publicado: (2008)

Phosphoglycerol-type wall and lipoteichoic acids are enantiomeric polymers differentiated by the stereospecific glycerophosphodiesterase GlpQ
por: Walter, Axel, et al.
Publicado: (2020)

Structural Analysis of Collagen Type I Interactions with Human Fibronectin Reveals a Cooperative Binding Mode
por: Erat, Michèle C., et al.
Publicado: (2013)

Early Murine T-lymphocyte Activation Is Accompanied by a Switch from N-Glycolyl- to N-Acetyl-neuraminic Acid and Generation of Ligands for Siglec-E
por: Redelinghuys, Pierre, et al.
Publicado: (2011)

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3(+) Dendritic Cells and a Subset of Monocytes
por: Huysamen, Cristal, et al.
Publicado: (2008)

Glycomic Characterization of Respiratory Tract Tissues of Ferrets: IMPLICATIONS FOR ITS USE IN INFLUENZA VIRUS INFECTION STUDIES
por: Jia, Nan, et al.
Publicado: (2014)

Cytokines Alter IgA1 O-Glycosylation by Dysregulating C1GalT1 and ST6GalNAc-II Enzymes
por: Suzuki, Hitoshi, et al.
Publicado: (2014)

Glycosylation at Asn(211) Regulates the Activation State of the Discoidin Domain Receptor 1 (DDR1)
por: Fu, Hsueh-Liang, et al.
Publicado: (2014)

Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis
por: Torres, Annabel, et al.
Publicado: (2017)

Mapping of Potent and Specific Binding Motifs, GLOGEN and GVOGEA, for Integrin α1β1 Using Collagen Toolkits II and III
por: Hamaia, Samir W., et al.
Publicado: (2012)

Development of a novel β-1,6-glucan–specific detection system using functionally-modified recombinant endo-β-1,6-glucanase
por: Yamanaka, Daisuke, et al.
Publicado: (2020)

Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-κB and expression of the long-noncoding RNA HAS2–AS1
por: Caon, Ilaria, et al.
Publicado: (2020)

A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-β-glucanase
por: Temple, Max J., et al.
Publicado: (2017)

Glycoprotein Biosynthesis in a Eukaryote Lacking the Membrane Protein Rft1
por: Jelk, Jennifer, et al.
Publicado: (2013)

Galectin-1 Regulates Tissue Exit of Specific Dendritic Cell Populations
por: Thiemann, Sandra, et al.
Publicado: (2015)

Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1
por: Wohl, Alexander P., et al.
Publicado: (2016)

Mapping the Effect of Gly Mutations in Collagen on α2β1 Integrin Binding
por: Yigit, Sezin, et al.
Publicado: (2016)

Role of the Netrin-like Domain of Procollagen C-Proteinase Enhancer-1 in the Control of Metalloproteinase Activity
por: Bekhouche, Mourad, et al.
Publicado: (2010)

Extended Binding Site on Fibronectin for the Functional Upstream Domain of Protein F1 of Streptococcus pyogenes
por: Maurer, Lisa M., et al.
Publicado: (2010)

Functional Similarities between the Protein O-Mannosyltransferases Pmt4 from Bakers' Yeast and Human POMT1
por: Bausewein, Daniela, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_gt89eev403nhfbdnof8sjnvpgi