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Structure and physicochemical characterization of a naproxen–picolinamide cocrystal

Naproxen (NPX) is a nonsteroidal anti-inflammatory drug with pain- and fever-relieving properties, currently marketed in the sodium salt form to overcome solubility problems; however, alternative solutions for improving its solubility across all pH values are desirable. NPX is suitable for cocrystal...

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Detalles Bibliográficos
Autores principales: Kerr, Hannah E., Softley, Lorna K., Suresh, Kuthuru, Hodgkinson, Paul, Evans, Ivana Radosavljevic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391861/
https://www.ncbi.nlm.nih.gov/pubmed/28257010
http://dx.doi.org/10.1107/S2053229616011980