Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge

Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC...

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Detalles Bibliográficos
Autor principal: Vergoulidou, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391981/
https://www.ncbi.nlm.nih.gov/pubmed/28469397
http://dx.doi.org/10.1177/1177271917695237
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author Vergoulidou, Maria
author_facet Vergoulidou, Maria
author_sort Vergoulidou, Maria
collection PubMed
description Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges.
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spelling pubmed-53919812017-05-03 Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge Vergoulidou, Maria Biomark Insights Case Report Leptomeningeal carcinomatosis (LC) is a rare and mainly secondary site of metastasis in solid tumors. In gastric cancer (GC), it is associated with a devastating prognosis, lacking an efficient and standardized treatment approach. We report a case of primary manifestation of LC due to metastatic GC with rapid deterioration and refractory course to conventional and intrathecal chemotherapy. We review the literature and discuss the therapeutic challenges. SAGE Publications 2017-03-16 /pmc/articles/PMC5391981/ /pubmed/28469397 http://dx.doi.org/10.1177/1177271917695237 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(http://www.uk.sagepub.com/aboutus/openaccess.htm).
spellingShingle Case Report
Vergoulidou, Maria
Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_full Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_fullStr Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_full_unstemmed Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_short Leptomeningeal Carcinomatosis in Gastric Cancer: A Therapeutical Challenge
title_sort leptomeningeal carcinomatosis in gastric cancer: a therapeutical challenge
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5391981/
https://www.ncbi.nlm.nih.gov/pubmed/28469397
http://dx.doi.org/10.1177/1177271917695237
work_keys_str_mv AT vergoulidoumaria leptomeningealcarcinomatosisingastriccanceratherapeuticalchallenge

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