Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway

The quality control of skeletal muscle is a continuous requirement throughout the lifetime, although its functions and quality present as a declining trend during aging process. Dysfunctional or deficient autophagy and excessive apoptosis may contribute to the atrophy of senescent skeletal muscle. S...

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Detalles Bibliográficos
Autores principales: Fan, Jingjing, Yang, Xiaoqi, Li, Jie, Shu, Ziyang, Dai, Jun, Liu, Xingran, Li, Biao, Jia, Shaohui, Kou, Xianjuan, Yang, Yi, Chen, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392263/
https://www.ncbi.nlm.nih.gov/pubmed/28407698
http://dx.doi.org/10.18632/oncotarget.15728

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