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Activated-PAK4 predicts worse prognosis in breast cancer and promotes tumorigenesis through activation of PI3K/AKT signaling

The p21-activated kinase 4 (PAK4) is sufficient to transform noncancerous mammary epithelial cells and to form tumors in the mammary glands of mice. The accumulated information suggests that PAK4 might be an oncogenic protein in breast cancer. In this study, we sought to identify the role for PAK4 i...

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Detalles Bibliográficos
Autores principales:	He, Li-Fang, Xu, Hong-Wu, Chen, Min, Xian, Zhi-Rong, Wen, Xiao-Fen, Chen, Min-Na, Du, Cai-Wen, Huang, Wen-He, Wu, Jun-Dong, Zhang, Guo-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392270/ https://www.ncbi.nlm.nih.gov/pubmed/28407679 http://dx.doi.org/10.18632/oncotarget.7466

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