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The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma

Drug repurposing is currently an important approach for accelerating drug discovery and development for clinical use. Hepatocellular carcinoma (HCC) presents drug resistance to chemotherapy, and the prognosis is poor due to the existence of liver cancer stem-like cells. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Chen, Jia-Jie, Cai, Nan, Chen, Guan-Zhong, Jia, Chang-Chang, Qiu, Dong-Bo, Du, Cong, Liu, Wei, Yang, Yang, Long, Zi-Jie, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392272/
https://www.ncbi.nlm.nih.gov/pubmed/26061710
http://dx.doi.org/10.18632/oncotarget.4307

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