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Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition

Runx1 is a well characterized transcription factor essential for hematopoietic differentiation and Runx1 mutations are the cause of leukemias. Runx1 is highly expressed in normal epithelium of most glands and recently has been associated with solid tumors. Notably, the function of Runx1 in the mamma...

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Detalles Bibliográficos
Autores principales: Hong, Deli, Messier, Terri L., Tye, Coralee E., Dobson, Jason R., Fritz, Andrew J., Sikora, Kenneth R., Browne, Gillian, Stein, Janet L., Lian, Jane B., Stein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392273/
https://www.ncbi.nlm.nih.gov/pubmed/28407681
http://dx.doi.org/10.18632/oncotarget.15381

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