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Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer

Persistent STAT3 activation is seen in many tumor cells and promotes malignant transformation. Here, we investigated whether capsazepine (Capz), a synthetic analogue of capsaicin, exerts anticancer effects by inhibiting STAT3 activation in prostate cancer cells. Capz inhibited both constitutive and...

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Detalles Bibliográficos
Autores principales:	Lee, Jong Hyun, Kim, Chulwon, Baek, Seung Ho, Ko, Jeong-Hyeon, Lee, Seok Geun, Yang, Woong Mo, Um, Jae-Young, Sethi, Gautam, Ahn, Kwang Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392279/ https://www.ncbi.nlm.nih.gov/pubmed/27458171 http://dx.doi.org/10.18632/oncotarget.10775

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