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Akt/mTOR mediated induction of bystander effect signaling in a nucleus independent manner in irradiated human lung adenocarcinoma epithelial cells

Cytoplasm is an important target for the radiation-induced bystander effect (RIBE). In the present work, the critical role of protein kinase B (Akt)/mammalian target of rapamycin (mTOR) pathway in the generation of RIBE signaling after X-ray irradiation and the rapid phosphorylation of Akt and mTOR...

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Detalles Bibliográficos
Autores principales: Li, Lu, Wang, Lu, Prise, Kevin M., Yu, K.N ., Chen, Guodong, Chen, Lianyun, Mei, Yide, Han, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392303/
https://www.ncbi.nlm.nih.gov/pubmed/28152510
http://dx.doi.org/10.18632/oncotarget.14931

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