Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells

Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and m...

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Detalles Bibliográficos
Autores principales: Okumura, Takashi, Ohuchida, Kenoki, Sada, Masafumi, Abe, Toshiya, Endo, Sho, Koikawa, Kazuhiro, Iwamoto, Chika, Miura, Daisuke, Mizuuchi, Yusuke, Moriyama, Taiki, Nakata, Kohei, Miyasaka, Yoshihiro, Manabe, Tatsuya, Ohtsuka, Takao, Nagai, Eishi, Mizumoto, Kazuhiro, Oda, Yoshinao, Hashizume, Makoto, Nakamura, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392327/
https://www.ncbi.nlm.nih.gov/pubmed/28407685
http://dx.doi.org/10.18632/oncotarget.15430

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