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NPC-26 kills human colorectal cancer cells via activating AMPK signaling

NPC-26 is novel mitochondrion-interfering compound. The current study tested its potential effect against colorectal cancer (CRC) cells. We demonstrated that NPC-26 induced potent anti-proliferative and cytotoxic activities against CRC cell lines (HCT-116, DLD-1 and HT-29). Activation of AMP-activat...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhen, Feng, Li, Wang, Jiqin, Cheng, Deshan, Liu, Mei, Ling, Meirong, Xu, Weiping, Sun, Keyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392330/ https://www.ncbi.nlm.nih.gov/pubmed/28407688 http://dx.doi.org/10.18632/oncotarget.15436

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