Cargando…

TET2 and MEG3 promoter methylation is associated with acute myeloid leukemia in a Hainan population

The promoter of MEG3, which encodes the long non-coding RNA (lncRNA) MEG3, is often hypermethylated in acute myeloid leukemia (AML). Additionally, the Tet methylcytosine dioxygenase 2 gene (TET2) is frequently inactivated, which can lead to impaired DNA methylation and promote AML development. We ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Hongxia, Duan, Mengling, Lin, Lie, Wu, Congming, Fu, Xiangjun, Wang, Hua, Guo, Li, Chen, Wenting, Huang, Li, Liu, Dan, Rao, Ruo, Wang, Shuwen, Ding, Yipeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392332/ https://www.ncbi.nlm.nih.gov/pubmed/28407691 http://dx.doi.org/10.18632/oncotarget.15440

Ejemplares similares

microRNA-22 can regulate expression of the long non-coding RNA MEG3 in acute myeloid leukemia
por: Yao, Hongxia, et al.
Publicado: (2017)

Spectrum of gene mutations identified by targeted next‐generation sequencing in Chinese leukemia patients
por: Yao, Hongxia, et al.
Publicado: (2020)

Expression and prognosis analysis of TET family in acute myeloid leukemia
por: Zhang, Tingjuan, et al.
Publicado: (2020)

The prognostic role of C-KIT, TET1 and TET2 gene expression in Acute Myeloid Leukemia
por: Nabil, Reem, et al.
Publicado: (2022)

Increased methylation upstream of the MEG3 promotor is observed in acute myeloid leukemia patients with better overall survival
por: Sellers, Zachariah Payne, et al.
Publicado: (2019)

Screening diagnostic markers for acute myeloid leukemia based on bioinformatics analysis
por: Chen, Wenting, et al.
Publicado: (2022)

Analysis of TET2 and EZH2 gene functions in chromosome instability in acute myeloid leukemia
por: Wang, Jingyi, et al.
Publicado: (2020)

Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
por: Jiang, Xi, et al.
Publicado: (2017)

The Prognostic Significance of TET2 Single Nucleotide Polymorphism in Egyptian Chronic Myeloid Leukemia
por: Hamed, Nahla A., et al.
Publicado: (2020)

Biallelic TET2 mutations confer sensitivity to 5′-azacitidine in acute myeloid leukemia
por: Stölzel, Friedrich, et al.
Publicado: (2023)

High Expression of TET1 Predicts Poor Survival in Cytogenetically Normal Acute Myeloid Leukemia From Two Cohorts
por: Wang, Jinghan, et al.
Publicado: (2018)

Assessment of Metalloid and Metal Contamination in Soils from Hainan, China
por: Liao, Xiangjun, et al.
Publicado: (2018)

TET2 mutations in acute myeloid leukemia: a comprehensive study in patients of Sindh, Pakistan
por: Shaikh, Abdul Rehman Khalil, et al.
Publicado: (2021)

Comprehensively analyze the expression and prognostic role for ten-eleven translocations (TETs) in acute myeloid leukemia
por: Huang, Yan, et al.
Publicado: (2020)

Acute loss of TET function results in aggressive myeloid cancer in mice
por: An, Jungeun, et al.
Publicado: (2015)

Characteristics of myeloid sarcoma in mice and patients with TET2 deficiency
por: Wang, Jinhuan, et al.
Publicado: (2020)

Characteristics of myeloid sarcoma in mice and patients with TET2 deficiency
por: Wang, Jinhuan, et al.
Publicado: (2020)

Long Noncoding RNA MEG3 Inhibits Cell Proliferation and Metastasis in Chronic Myeloid Leukemia via Targeting miR-184
por: Li, Jingdong, et al.
Publicado: (2018)

Author Correction: Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
por: Jiang, Xi, et al.
Publicado: (2018)

The prognostic impact of tet oncogene family member 2 mutations in patients with acute myeloid leukemia: a systematic-review and meta-analysis
por: Wang, Ruiqi, et al.
Publicado: (2019)

Molecular epidemiology and antibiotic resistance of Burkholderia pseudomallei isolates from Hainan, China: A STROBE compliant observational study
por: Rao, Chenglong, et al.
Publicado: (2019)

The correlation between CYP4F2 variants and chronic obstructive pulmonary disease risk in Hainan Han population
por: Ding, Yipeng, et al.
Publicado: (2020)

Loss of TET2 and TET3 in regulatory T cells unleashes effector function
por: Yue, Xiaojing, et al.
Publicado: (2019)

TET2 Overexpression in Chronic Lymphocytic Leukemia Is Unrelated to the Presence of TET2 Variations
por: Hernández-Sánchez, María, et al.
Publicado: (2014)

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
por: Ko, Myunggon, et al.
Publicado: (2010)

Clinical Implication of DNMT3A and TET2 Genes Mutations in Cytogenetically Normal Acute Myeloid Leukemia
por: Aref, Salah, et al.
Publicado: (2022)

TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
por: Heyes, Elizabeth, et al.
Publicado: (2023)

Detection of prognostic methylation markers by methylC-capture sequencing in acute myeloid leukemia
por: Li, Yan, et al.
Publicado: (2017)

Methylation status of DDIT3 gene in Chronic Myeloid Leukemia
por: Wang, Ya-li, et al.
Publicado: (2010)

Assessment of groundwater hydrochemistry, water quality, and health risk in Hainan Island, China
por: Hou, Qingqin, et al.
Publicado: (2023)

TET2 Loss Dysregulates the Behavior of Bone Marrow Mesenchymal Stromal Cells and Accelerates Tet2(−/−)-Driven Myeloid Malignancy Progression
por: Li, Rong, et al.
Publicado: (2017)

The Long Noncoding RNA MEG3 and its Target miR-147 Regulate JAK/STAT Pathway in Advanced Chronic Myeloid Leukemia
por: Li, Zi-ye, et al.
Publicado: (2018)

Characterization of Colletotrichum Species Infecting Litchi in Hainan, China
por: Cao, Xueren, et al.
Publicado: (2023)

LncRNA MEG3 Regulates Imatinib Resistance in Chronic Myeloid Leukemia via Suppressing MicroRNA-21
por: Zhou, Xiangyu, et al.
Publicado: (2017)

TET2 Promoter DNA Methylation and Expression Analysis in Pediatric B-cell Acute Lymphoblastic Leukemia
por: Musialik, Ewa, et al.
Publicado: (2014)

Advances in the DNA methylation hydroxylase TET1
por: Liu, Wenzheng, et al.
Publicado: (2021)

Methylation of SPRED1: A New Target in Acute Myeloid Leukemia
por: Su, Nan, et al.
Publicado: (2022)

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1
por: Das, Andrew B., et al.
Publicado: (2019)

Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development
por: Qi, Qi, et al.
Publicado: (2022)

Determination of the evolutionary pressure on Camellia oleifera on Hainan Island using the complete chloroplast genome sequence
por: Zhang, Wan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6mtacgn6g3bq3ld5bmn80ebpcl