Cargando…

Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda

Introduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic...

Descripción completa

Detalles Bibliográficos
Autores principales: Musomba, Rachel, Mubiru, Frank, Nakalema, Shadia, Mackline, Hope, Kalule, Ivan, Kiragga, Agnes N., Ratanshi, Rosalind Parkes, Castelnuovo, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392405/
https://www.ncbi.nlm.nih.gov/pubmed/28469942
http://dx.doi.org/10.1155/2017/3527563
_version_ 1783229442532835328
author Musomba, Rachel
Mubiru, Frank
Nakalema, Shadia
Mackline, Hope
Kalule, Ivan
Kiragga, Agnes N.
Ratanshi, Rosalind Parkes
Castelnuovo, Barbara
author_facet Musomba, Rachel
Mubiru, Frank
Nakalema, Shadia
Mackline, Hope
Kalule, Ivan
Kiragga, Agnes N.
Ratanshi, Rosalind Parkes
Castelnuovo, Barbara
author_sort Musomba, Rachel
collection PubMed
description Introduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic from January 2012 to 31st July 2014, while the follow up period extended up to October 30th 2015. LTP was defined as being out of care for ≥3 months. Results. Overall 856 women were included. Only 36.4% (86/236) of the women were enrolled in the first trimester. Overall 69 (8.1%) were LTP. In the multivariate analysis older women (HR: 0.80 per five-year increase, CI: 0.64–1.0, and P = 0.060) and women on ART at the time of pregnancy (0.58, CI: 0.34–0.98, and P = 0.040) were more likely not to be LTP. Among women already on ART at the time of pregnancy no factor was associated with LTP. Conclusion. Our results suggest the need for interventions to enhance prompt linkage of HIV positive women to HIV services for ART initiation and for increased retention particularly in young and ART naive women.
format Online
Article
Text
id pubmed-5392405
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-53924052017-05-03 Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda Musomba, Rachel Mubiru, Frank Nakalema, Shadia Mackline, Hope Kalule, Ivan Kiragga, Agnes N. Ratanshi, Rosalind Parkes Castelnuovo, Barbara AIDS Res Treat Research Article Introduction. We aim to describe the time of entry into care and factors associated with being lost to program (LTP) in pregnant women on Option B Plus in an integrated HIV and antenatal care (ANC) clinic in Uganda. Methods. We included all pregnant women enrolled into the integrated HIV-ANC clinic from January 2012 to 31st July 2014, while the follow up period extended up to October 30th 2015. LTP was defined as being out of care for ≥3 months. Results. Overall 856 women were included. Only 36.4% (86/236) of the women were enrolled in the first trimester. Overall 69 (8.1%) were LTP. In the multivariate analysis older women (HR: 0.80 per five-year increase, CI: 0.64–1.0, and P = 0.060) and women on ART at the time of pregnancy (0.58, CI: 0.34–0.98, and P = 0.040) were more likely not to be LTP. Among women already on ART at the time of pregnancy no factor was associated with LTP. Conclusion. Our results suggest the need for interventions to enhance prompt linkage of HIV positive women to HIV services for ART initiation and for increased retention particularly in young and ART naive women. Hindawi 2017 2017-04-02 /pmc/articles/PMC5392405/ /pubmed/28469942 http://dx.doi.org/10.1155/2017/3527563 Text en Copyright © 2017 Rachel Musomba et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Musomba, Rachel
Mubiru, Frank
Nakalema, Shadia
Mackline, Hope
Kalule, Ivan
Kiragga, Agnes N.
Ratanshi, Rosalind Parkes
Castelnuovo, Barbara
Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_full Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_fullStr Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_full_unstemmed Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_short Describing Point of Entry into Care and Being Lost to Program in a Cohort of HIV Positive Pregnant Women in a Large Urban Centre in Uganda
title_sort describing point of entry into care and being lost to program in a cohort of hiv positive pregnant women in a large urban centre in uganda
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392405/
https://www.ncbi.nlm.nih.gov/pubmed/28469942
http://dx.doi.org/10.1155/2017/3527563
work_keys_str_mv AT musombarachel describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT mubirufrank describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT nakalemashadia describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT macklinehope describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT kaluleivan describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT kiraggaagnesn describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT ratanshirosalindparkes describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda
AT castelnuovobarbara describingpointofentryintocareandbeinglosttoprograminacohortofhivpositivepregnantwomeninalargeurbancentreinuganda