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Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392407/ https://www.ncbi.nlm.nih.gov/pubmed/28469944 http://dx.doi.org/10.1155/2017/9092576 |
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author | Português, João Calvo, Lucy Oliveira, Margarida Pereira, Vítor Hugo Guardado, Joana Lourenço, Mário Rui Azevedo, Olga Ferreira, Francisco Canário-Almeida, Filipa Lourenço, António |
author_facet | Português, João Calvo, Lucy Oliveira, Margarida Pereira, Vítor Hugo Guardado, Joana Lourenço, Mário Rui Azevedo, Olga Ferreira, Francisco Canário-Almeida, Filipa Lourenço, António |
author_sort | Português, João |
collection | PubMed |
description | Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit within the right heart. Optimal management of RHT is still uncertain. A 79-year-old woman, with a history of recent total hysterectomy with adnexectomy and a Wells procedure, presented to the emergency department following an episode of syncope. Computed tomography revealed bilateral PE and the presence of a right atrial thrombus. Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. Subsequent clinical improvement was observed and echocardiographic follow-up revealed complete thrombus dissolution and complete recovery of right ventricle function. Most authors recommend treatment of PE with RHT with thrombolysis or embolectomy followed by anticoagulation, although evidence is scarce. Individual risk of hemorrhage and operatory-related mortality should be taken into account when defining the treatment strategy especially when benefit is not firmly established. |
format | Online Article Text |
id | pubmed-5392407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-53924072017-05-03 Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome Português, João Calvo, Lucy Oliveira, Margarida Pereira, Vítor Hugo Guardado, Joana Lourenço, Mário Rui Azevedo, Olga Ferreira, Francisco Canário-Almeida, Filipa Lourenço, António Case Rep Cardiol Case Report Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit within the right heart. Optimal management of RHT is still uncertain. A 79-year-old woman, with a history of recent total hysterectomy with adnexectomy and a Wells procedure, presented to the emergency department following an episode of syncope. Computed tomography revealed bilateral PE and the presence of a right atrial thrombus. Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. Subsequent clinical improvement was observed and echocardiographic follow-up revealed complete thrombus dissolution and complete recovery of right ventricle function. Most authors recommend treatment of PE with RHT with thrombolysis or embolectomy followed by anticoagulation, although evidence is scarce. Individual risk of hemorrhage and operatory-related mortality should be taken into account when defining the treatment strategy especially when benefit is not firmly established. Hindawi 2017 2017-04-02 /pmc/articles/PMC5392407/ /pubmed/28469944 http://dx.doi.org/10.1155/2017/9092576 Text en Copyright © 2017 João Português et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Português, João Calvo, Lucy Oliveira, Margarida Pereira, Vítor Hugo Guardado, Joana Lourenço, Mário Rui Azevedo, Olga Ferreira, Francisco Canário-Almeida, Filipa Lourenço, António Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome |
title | Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome |
title_full | Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome |
title_fullStr | Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome |
title_full_unstemmed | Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome |
title_short | Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome |
title_sort | pulmonary embolism and intracardiac type a thrombus with an unexpected outcome |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392407/ https://www.ncbi.nlm.nih.gov/pubmed/28469944 http://dx.doi.org/10.1155/2017/9092576 |
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