Cargando…

Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome

Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit...

Descripción completa

Detalles Bibliográficos
Autores principales: Português, João, Calvo, Lucy, Oliveira, Margarida, Pereira, Vítor Hugo, Guardado, Joana, Lourenço, Mário Rui, Azevedo, Olga, Ferreira, Francisco, Canário-Almeida, Filipa, Lourenço, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392407/
https://www.ncbi.nlm.nih.gov/pubmed/28469944
http://dx.doi.org/10.1155/2017/9092576
_version_ 1783229443071803392
author Português, João
Calvo, Lucy
Oliveira, Margarida
Pereira, Vítor Hugo
Guardado, Joana
Lourenço, Mário Rui
Azevedo, Olga
Ferreira, Francisco
Canário-Almeida, Filipa
Lourenço, António
author_facet Português, João
Calvo, Lucy
Oliveira, Margarida
Pereira, Vítor Hugo
Guardado, Joana
Lourenço, Mário Rui
Azevedo, Olga
Ferreira, Francisco
Canário-Almeida, Filipa
Lourenço, António
author_sort Português, João
collection PubMed
description Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit within the right heart. Optimal management of RHT is still uncertain. A 79-year-old woman, with a history of recent total hysterectomy with adnexectomy and a Wells procedure, presented to the emergency department following an episode of syncope. Computed tomography revealed bilateral PE and the presence of a right atrial thrombus. Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. Subsequent clinical improvement was observed and echocardiographic follow-up revealed complete thrombus dissolution and complete recovery of right ventricle function. Most authors recommend treatment of PE with RHT with thrombolysis or embolectomy followed by anticoagulation, although evidence is scarce. Individual risk of hemorrhage and operatory-related mortality should be taken into account when defining the treatment strategy especially when benefit is not firmly established.
format Online
Article
Text
id pubmed-5392407
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-53924072017-05-03 Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome Português, João Calvo, Lucy Oliveira, Margarida Pereira, Vítor Hugo Guardado, Joana Lourenço, Mário Rui Azevedo, Olga Ferreira, Francisco Canário-Almeida, Filipa Lourenço, António Case Rep Cardiol Case Report Detection of right heart thrombi (RHT) in the context of pulmonary thromboembolism (PE) is uncommon (4–18%) and increases the risk of mortality beyond the presence of PE alone. Type A thrombi are serpiginous and highly mobile and are thought to be originated from large veins and captured in-transit within the right heart. Optimal management of RHT is still uncertain. A 79-year-old woman, with a history of recent total hysterectomy with adnexectomy and a Wells procedure, presented to the emergency department following an episode of syncope. Computed tomography revealed bilateral PE and the presence of a right atrial thrombus. Transthoracic echocardiography demonstrated a free-floating type A thrombus in the right atrium, protruding into the right ventricle, and signs of pulmonary hypertension and right ventricle dysfunction. Considering the recent surgery and clinical stability, treatment with heparin alone was decided. Subsequent clinical improvement was observed and echocardiographic follow-up revealed complete thrombus dissolution and complete recovery of right ventricle function. Most authors recommend treatment of PE with RHT with thrombolysis or embolectomy followed by anticoagulation, although evidence is scarce. Individual risk of hemorrhage and operatory-related mortality should be taken into account when defining the treatment strategy especially when benefit is not firmly established. Hindawi 2017 2017-04-02 /pmc/articles/PMC5392407/ /pubmed/28469944 http://dx.doi.org/10.1155/2017/9092576 Text en Copyright © 2017 João Português et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Português, João
Calvo, Lucy
Oliveira, Margarida
Pereira, Vítor Hugo
Guardado, Joana
Lourenço, Mário Rui
Azevedo, Olga
Ferreira, Francisco
Canário-Almeida, Filipa
Lourenço, António
Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_full Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_fullStr Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_full_unstemmed Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_short Pulmonary Embolism and Intracardiac Type A Thrombus with an Unexpected Outcome
title_sort pulmonary embolism and intracardiac type a thrombus with an unexpected outcome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392407/
https://www.ncbi.nlm.nih.gov/pubmed/28469944
http://dx.doi.org/10.1155/2017/9092576
work_keys_str_mv AT portuguesjoao pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT calvolucy pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT oliveiramargarida pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT pereiravitorhugo pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT guardadojoana pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT lourencomariorui pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT azevedoolga pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT ferreirafrancisco pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT canarioalmeidafilipa pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome
AT lourencoantonio pulmonaryembolismandintracardiactypeathrombuswithanunexpectedoutcome