Age-Associated Microbial Dysbiosis Promotes Intestinal Permeability, Systemic Inflammation, and Macrophage Dysfunction

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Levels of inflammatory mediators in circulation are known to increase with age, but the underlying cause of this age-associated inflammation is debated. We find that, when maintained under germ-free conditions, mice do not display an age-related increase in circulating pro-inflammatory cytokine leve...

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Detalles Bibliográficos
Autores principales: Thevaranjan, Netusha, Puchta, Alicja, Schulz, Christian, Naidoo, Avee, Szamosi, J.C., Verschoor, Chris P., Loukov, Dessi, Schenck, Louis P., Jury, Jennifer, Foley, Kevin P., Schertzer, Jonathan D., Larché, Maggie J., Davidson, Donald J., Verdú, Elena F., Surette, Michael G., Bowdish, Dawn M.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392495/
https://www.ncbi.nlm.nih.gov/pubmed/28407483
http://dx.doi.org/10.1016/j.chom.2017.03.002
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