Cargando…
Rheumatoid arthritis: what do MRI and ultrasound show
Rheumatoid arthritis is the most common inflammatory arthritis, affecting approximately 1% of the world’s population. Its pathogenesis has not been completely understood. However, there is evidence that the disease may involve synovial joints, subchondral bone marrow as well as intra- and extraartic...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medical Communications Sp. z o.o.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392548/ https://www.ncbi.nlm.nih.gov/pubmed/28439423 http://dx.doi.org/10.15557/JoU.2017.0001 |
_version_ | 1783229468237627392 |
---|---|
author | Sudoł-Szopińska, Iwona Jans, Lennart Teh, James |
author_facet | Sudoł-Szopińska, Iwona Jans, Lennart Teh, James |
author_sort | Sudoł-Szopińska, Iwona |
collection | PubMed |
description | Rheumatoid arthritis is the most common inflammatory arthritis, affecting approximately 1% of the world’s population. Its pathogenesis has not been completely understood. However, there is evidence that the disease may involve synovial joints, subchondral bone marrow as well as intra- and extraarticular fat tissue, and may lead to progressive joint destruction and disability. Over the last two decades, significant improvement in its prognosis has been achieved owing to new strategies for disease management, the emergence of new biologic therapies and better utilization of conventional disease-modifying antirheumatic drugs. Prompt diagnosis and appropriate therapy have been recognized as essential for improving clinical outcomes in patients with early rheumatoid arthritis. Despite the potential of ultrasonography and magnetic resonance imaging to visualize all tissues typically involved in the pathogenesis of rheumatoid arthritis, the diagnosis of early disease remains difficult due to limited specificity of findings. This paper summarizes the pathogenesis phenomena of rheumatoid arthritis and describes rheumatoid arthritis-related features of the disease within the synovium, subchondral bone marrow and articular fat tissue on MRI and ultrasound. Moreover, the paper aims to illustrate the significance of MRI and ultrasound findings in rheumatoid arthritis in the diagnosis of subclinical and early inflammation, and the importance of MRI and US in the follow-up and establishing remission. Finally, we also discuss MRI of the spine in rheumatoid arthritis, which may help assess the presence of active inflammation and complications. |
format | Online Article Text |
id | pubmed-5392548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medical Communications Sp. z o.o. |
record_format | MEDLINE/PubMed |
spelling | pubmed-53925482017-04-24 Rheumatoid arthritis: what do MRI and ultrasound show Sudoł-Szopińska, Iwona Jans, Lennart Teh, James J Ultrason Editorial Rheumatoid arthritis is the most common inflammatory arthritis, affecting approximately 1% of the world’s population. Its pathogenesis has not been completely understood. However, there is evidence that the disease may involve synovial joints, subchondral bone marrow as well as intra- and extraarticular fat tissue, and may lead to progressive joint destruction and disability. Over the last two decades, significant improvement in its prognosis has been achieved owing to new strategies for disease management, the emergence of new biologic therapies and better utilization of conventional disease-modifying antirheumatic drugs. Prompt diagnosis and appropriate therapy have been recognized as essential for improving clinical outcomes in patients with early rheumatoid arthritis. Despite the potential of ultrasonography and magnetic resonance imaging to visualize all tissues typically involved in the pathogenesis of rheumatoid arthritis, the diagnosis of early disease remains difficult due to limited specificity of findings. This paper summarizes the pathogenesis phenomena of rheumatoid arthritis and describes rheumatoid arthritis-related features of the disease within the synovium, subchondral bone marrow and articular fat tissue on MRI and ultrasound. Moreover, the paper aims to illustrate the significance of MRI and ultrasound findings in rheumatoid arthritis in the diagnosis of subclinical and early inflammation, and the importance of MRI and US in the follow-up and establishing remission. Finally, we also discuss MRI of the spine in rheumatoid arthritis, which may help assess the presence of active inflammation and complications. Medical Communications Sp. z o.o. 2017-03-31 2017-03 /pmc/articles/PMC5392548/ /pubmed/28439423 http://dx.doi.org/10.15557/JoU.2017.0001 Text en 2017 Polish Ultrasound Society. Published by Medical Communications Sp. z o.o. All rights reserved. http://creativecommons.org/licenses/by-nc-nd This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (CC BY-NC-ND). Reproduction is permitted for personal, educational, non-commercial use, provided that the original article is in whole, unmodified, and properly cited. |
spellingShingle | Editorial Sudoł-Szopińska, Iwona Jans, Lennart Teh, James Rheumatoid arthritis: what do MRI and ultrasound show |
title | Rheumatoid arthritis: what do MRI and ultrasound show |
title_full | Rheumatoid arthritis: what do MRI and ultrasound show |
title_fullStr | Rheumatoid arthritis: what do MRI and ultrasound show |
title_full_unstemmed | Rheumatoid arthritis: what do MRI and ultrasound show |
title_short | Rheumatoid arthritis: what do MRI and ultrasound show |
title_sort | rheumatoid arthritis: what do mri and ultrasound show |
topic | Editorial |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392548/ https://www.ncbi.nlm.nih.gov/pubmed/28439423 http://dx.doi.org/10.15557/JoU.2017.0001 |
work_keys_str_mv | AT sudołszopinskaiwona rheumatoidarthritiswhatdomriandultrasoundshow AT janslennart rheumatoidarthritiswhatdomriandultrasoundshow AT tehjames rheumatoidarthritiswhatdomriandultrasoundshow |