Cyclin F/FBXO1 Interacts with HIV-1 Viral Infectivity Factor (Vif) and Restricts Progeny Virion Infectivity by Ubiquitination and Proteasomal Degradation of Vif Protein through SCF(cyclin F) E3 Ligase Machinery

Cyclin F protein, also known as FBXO1, is the largest among all cyclins and oscillates in the cell cycle like other cyclins. Apart from being a G(2)/M cyclin, cyclin F functions as the substrate-binding subunit of SCF(cyclin F) E3 ubiquitin ligase. In a gene expression analysis performed to identify...

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Detalles Bibliográficos
Autores principales: Augustine, Tracy, Chaudhary, Priyanka, Gupta, Kailash, Islam, Sehbanul, Ghosh, Payel, Santra, Manas Kumar, Mitra, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392680/
https://www.ncbi.nlm.nih.gov/pubmed/28184007
http://dx.doi.org/10.1074/jbc.M116.765842

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