Altered protein dynamics of disease-associated lamin A mutants

BACKGROUND: Recent interest in the function of the nuclear lamina has been provoked by the discovery of lamin A/C mutations in the laminopathy diseases. However, it is not understood why mutations in lamin A give such a range of tissue-specific phenotypes. Part of the problem in rationalising genoty...

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Detalles Bibliográficos
Autores principales: Gilchrist, Susan, Gilbert, Nick, Perry, Paul, Östlund, Cecilia, Worman, Howard J, Bickmore, Wendy A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539277/
https://www.ncbi.nlm.nih.gov/pubmed/15596010
http://dx.doi.org/10.1186/1471-2121-5-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC539277/
https://www.ncbi.nlm.nih.gov/pubmed/15596010
http://dx.doi.org/10.1186/1471-2121-5-46

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