Large is required for normal astrocyte migration and retinal vasculature development

BACKGROUND: Persistent fetal vasculature (PFV) is a congenital developmental anomaly of the eye that accounts for about 5% of childhood blindness. The molecular mechanism of PFV remains unclear. As a glycosyltransferase of α-dystroglycan, LARGE mutations have been found in congenital muscular dystro...

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Detalles Bibliográficos
Autores principales: Zhou, Min, Wang, Herui, Ren, Hui, Jiang, Rui, Zhang, Chi, Wu, Xiaohui, Xu, Gezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392960/
https://www.ncbi.nlm.nih.gov/pubmed/28428837
http://dx.doi.org/10.1186/s13578-017-0143-9

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