Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs

BACKGROUND: Estrogen and progesterone are potent breast mitogens. In addition to steroid hormones, multiple signaling pathways input to estrogen receptor (ER) and progesterone receptor (PR) actions via posttranslational events. Protein kinases commonly activated in breast cancers phosphorylate stero...

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Detalles Bibliográficos
Autores principales: Knutson, Todd P., Truong, Thu H., Ma, Shihong, Brady, Nicholas J., Sullivan, Megan E., Raj, Ganesh, Schwertfeger, Kathryn L., Lange, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392969/
https://www.ncbi.nlm.nih.gov/pubmed/28412963
http://dx.doi.org/10.1186/s13045-017-0462-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392969/
https://www.ncbi.nlm.nih.gov/pubmed/28412963
http://dx.doi.org/10.1186/s13045-017-0462-7

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