The telomeric DNA damage response occurs in the absence of chromatin decompaction

Telomeres are specialized nucleoprotein structures that protect chromosome ends from DNA damage response (DDR) and DNA rearrangements. The telomeric shelterin protein TRF2 suppresses the DDR, and this function has been attributed to its abilities to trigger t-loop formation or prevent massive decomp...

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Detalles Bibliográficos
Autores principales: Vancevska, Aleksandra, Douglass, Kyle M., Pfeiffer, Verena, Manley, Suliana, Lingner, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393052/
https://www.ncbi.nlm.nih.gov/pubmed/28381410
http://dx.doi.org/10.1101/gad.294082.116

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