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A novel role of the Dna2 translocase function in DNA break resection

DNA double-strand break repair by homologous recombination entails nucleolytic resection of the 5′ strand at break ends. Dna2, a flap endonuclease with 5′–3′ helicase activity, is involved in the resection process. The Dna2 helicase activity has been implicated in Okazaki fragment processing during...

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Detalles Bibliográficos
Autores principales:	Miller, Adam S., Daley, James M., Pham, Nhung Tuyet, Niu, Hengyao, Xue, Xiaoyu, Ira, Grzegorz, Sung, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393064/ https://www.ncbi.nlm.nih.gov/pubmed/28336516 http://dx.doi.org/10.1101/gad.295659.116

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