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Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma

The Asp358Ala variant in the interleukin-6 receptor (IL-6R) gene has been implicated in asthma, autoimmune and cardiovascular disorders, but its role in other respiratory conditions such as chronic obstructive pulmonary disease (COPD) has not been investigated. The aims of this study were to evaluat...

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Detalles Bibliográficos
Autores principales:	Farahi, Neda, Paige, Ellie, Balla, Jozef, Prudence, Emily, Ferreira, Ricardo C., Southwood, Mark, Appleby, Sarah L., Bakke, Per, Gulsvik, Amund, Litonjua, Augusto A., Sparrow, David, Silverman, Edwin K., Cho, Michael H., Danesh, John, Paul, Dirk S., Freitag, Daniel F., Chilvers, Edwin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Association Studies Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393150/ https://www.ncbi.nlm.nih.gov/pubmed/28334838 http://dx.doi.org/10.1093/hmg/ddx053

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