Pseudouridine and N(6)-methyladenosine modifications weaken PUF protein/RNA interactions

RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant noncoding RNA such as tRNA and rRNA, the advent of sensitive sequencing-based approaches has led to the discovery of extensive and regulated modifi...

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Detalles Bibliográficos
Autores principales: Vaidyanathan, Pavanapuresan P., AlSadhan, Ishraq, Merriman, Dawn K., Al-Hashimi, Hashim M., Herschlag, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393172/
https://www.ncbi.nlm.nih.gov/pubmed/28138061
http://dx.doi.org/10.1261/rna.060053.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393172/
https://www.ncbi.nlm.nih.gov/pubmed/28138061
http://dx.doi.org/10.1261/rna.060053.116

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