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Pseudouridine and N(6)-methyladenosine modifications weaken PUF protein/RNA interactions
RNA modifications are ubiquitous in biology, with over 100 distinct modifications. While the vast majority were identified and characterized on abundant noncoding RNA such as tRNA and rRNA, the advent of sensitive sequencing-based approaches has led to the discovery of extensive and regulated modifi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393172/ https://www.ncbi.nlm.nih.gov/pubmed/28138061 http://dx.doi.org/10.1261/rna.060053.116 |