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Translation of poly(A) tails leads to precise mRNA cleavage
Translation of poly(A) tails leads to mRNA cleavage but the mechanism and global pervasiveness of this “nonstop/no-go” decay process is not understood. Here we performed ribosome profiling (in a yeast strain lacking exosome function) of short 15–18 nucleotides mRNA footprints to identify ribosomes s...
Autores principales: | Guydosh, Nicholas R., Green, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393183/ https://www.ncbi.nlm.nih.gov/pubmed/28193672 http://dx.doi.org/10.1261/rna.060418.116 |
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