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Norovirus-Mediated Modification of the Translational Landscape via Virus and Host-Induced Cleavage of Translation Initiation Factors

Noroviruses produce viral RNAs lacking a 5′ cap structure and instead use a virus-encoded viral protein genome-linked (VPg) protein covalently linked to viral RNA to interact with translation initiation factors and drive viral protein synthesis. Norovirus infection results in the induction of the in...

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Detalles Bibliográficos
Autores principales: Emmott, Edward, Sorgeloos, Frederic, Caddy, Sarah L., Vashist, Surender, Sosnovtsev, Stanislav, Lloyd, Richard, Heesom, Kate, Locker, Nicolas, Goodfellow, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393397/
https://www.ncbi.nlm.nih.gov/pubmed/28087593
http://dx.doi.org/10.1074/mcp.M116.062448