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Sequence dependency of canonical base pair opening in the DNA double helix
The flipping-out of a DNA base from the double helical structure is a key step of many cellular processes, such as DNA replication, modification and repair. Base pair opening is the first step of base flipping and the exact mechanism is still not well understood. We investigate sequence effects on b...
Autores principales: | Lindahl, Viveca, Villa, Alessandra, Hess, Berk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393899/ https://www.ncbi.nlm.nih.gov/pubmed/28369121 http://dx.doi.org/10.1371/journal.pcbi.1005463 |
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