Cargando…
Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature
Posttubercular adhesive arachnoiditis is a rare, late complication of tubercular meningitis. Syringomyelia can develop as a consequence of intramedullary cystic lesions and cerebrospinal fluid (CSF) flow disturbance around the spinal cord, even after successful chemotherapy. We reviewed the literatu...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393916/ https://www.ncbi.nlm.nih.gov/pubmed/28428929 http://dx.doi.org/10.1055/s-0037-1601327 |
_version_ | 1783229662900518912 |
---|---|
author | Canova, Giuseppe Boaro, Alessandro Giordan, Enrico Longatti, Pierluigi |
author_facet | Canova, Giuseppe Boaro, Alessandro Giordan, Enrico Longatti, Pierluigi |
author_sort | Canova, Giuseppe |
collection | PubMed |
description | Posttubercular adhesive arachnoiditis is a rare, late complication of tubercular meningitis. Syringomyelia can develop as a consequence of intramedullary cystic lesions and cerebrospinal fluid (CSF) flow disturbance around the spinal cord, even after successful chemotherapy. We reviewed the literature related to posttubercular syringomyelia treatment and suggest a new combined surgical approach. A 25-year-old Nigerian male patient presented with legs numbness, urinary disturbance, and legs weakness. Spinal magnetic resonance revealed a T5-T7 syringomyelia, secondary to adhesive spinal arachnoiditis related to a history of tuberculous meningitis. Adhesiolysis by direct visualization with a flexible endoscope was performed and a handmade S-italic syringe-subdural shunt was placed to restore CSF flow. During the postoperative course, the neurological deficits improved together with the resolution of the syrinx. Long-term magnetic resonance imaging follow-up documented no recurrences or shunt displacements. We suggest that, when antitubercular therapy is not effective to resolve postarachnoiditis syrinx, arachnolysis with a flexible endoscope together with the placement of an S-italic shunt allowed free CSF communication between the syrinx and the subarachnoid space. Furthermore, we support that the use of an s-shaped shunt could prevent displacement or migration of the device and allows an easier revision in case of acute or late complications. |
format | Online Article Text |
id | pubmed-5393916 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-53939162017-04-20 Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature Canova, Giuseppe Boaro, Alessandro Giordan, Enrico Longatti, Pierluigi J Neurol Surg Rep Posttubercular adhesive arachnoiditis is a rare, late complication of tubercular meningitis. Syringomyelia can develop as a consequence of intramedullary cystic lesions and cerebrospinal fluid (CSF) flow disturbance around the spinal cord, even after successful chemotherapy. We reviewed the literature related to posttubercular syringomyelia treatment and suggest a new combined surgical approach. A 25-year-old Nigerian male patient presented with legs numbness, urinary disturbance, and legs weakness. Spinal magnetic resonance revealed a T5-T7 syringomyelia, secondary to adhesive spinal arachnoiditis related to a history of tuberculous meningitis. Adhesiolysis by direct visualization with a flexible endoscope was performed and a handmade S-italic syringe-subdural shunt was placed to restore CSF flow. During the postoperative course, the neurological deficits improved together with the resolution of the syrinx. Long-term magnetic resonance imaging follow-up documented no recurrences or shunt displacements. We suggest that, when antitubercular therapy is not effective to resolve postarachnoiditis syrinx, arachnolysis with a flexible endoscope together with the placement of an S-italic shunt allowed free CSF communication between the syrinx and the subarachnoid space. Furthermore, we support that the use of an s-shaped shunt could prevent displacement or migration of the device and allows an easier revision in case of acute or late complications. Georg Thieme Verlag KG 2017-04 /pmc/articles/PMC5393916/ /pubmed/28428929 http://dx.doi.org/10.1055/s-0037-1601327 Text en © Thieme Medical Publishers |
spellingShingle | Canova, Giuseppe Boaro, Alessandro Giordan, Enrico Longatti, Pierluigi Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature |
title | Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature |
title_full | Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature |
title_fullStr | Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature |
title_full_unstemmed | Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature |
title_short | Treatment of Posttubercular Syringomyelia Not Responsive to Antitubercular Therapy: Case Report and Review of Literature |
title_sort | treatment of posttubercular syringomyelia not responsive to antitubercular therapy: case report and review of literature |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393916/ https://www.ncbi.nlm.nih.gov/pubmed/28428929 http://dx.doi.org/10.1055/s-0037-1601327 |
work_keys_str_mv | AT canovagiuseppe treatmentofposttubercularsyringomyelianotresponsivetoantituberculartherapycasereportandreviewofliterature AT boaroalessandro treatmentofposttubercularsyringomyelianotresponsivetoantituberculartherapycasereportandreviewofliterature AT giordanenrico treatmentofposttubercularsyringomyelianotresponsivetoantituberculartherapycasereportandreviewofliterature AT longattipierluigi treatmentofposttubercularsyringomyelianotresponsivetoantituberculartherapycasereportandreviewofliterature |