mTORC1 and mTORC2 in cancer and the tumor microenvironment

The mammalian target of rapamycin (mTOR) is a crucial signaling node that integrates environmental cues to regulate cell survival, proliferation, and metabolism, and is often deregulated in human cancer. mTOR kinase acts in two functionally distinct complexes, mTOR complex 1 (mTORC1) and 2 (mTORC2),...

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Detalles Bibliográficos
Autores principales: Kim, Laura C., Cook, Rebecca S., Chen, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393956/
https://www.ncbi.nlm.nih.gov/pubmed/27748764
http://dx.doi.org/10.1038/onc.2016.363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393956/
https://www.ncbi.nlm.nih.gov/pubmed/27748764
http://dx.doi.org/10.1038/onc.2016.363

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