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Leydig cell tumor in grey zone: A case report
INTRODUCTION: Leydig cell tumor constitutes only about 1–3% of testicular neoplasms. There is apparently increased incidence in the last few years; one possible explanation for this phenomenon is the widespread use of ultrasound technology and the subsequent increased early detection of smaller lesi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394201/ https://www.ncbi.nlm.nih.gov/pubmed/28419904 http://dx.doi.org/10.1016/j.ijscr.2017.03.043 |
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author | Muheilan, Muheilan Mustafa Shomaf, Maha Tarawneh, Emad Murshidi, Muayyad Mujalli Al-Sayyed, Manar Rizik Murshidi, Mujalli Mhailan |
author_facet | Muheilan, Muheilan Mustafa Shomaf, Maha Tarawneh, Emad Murshidi, Muayyad Mujalli Al-Sayyed, Manar Rizik Murshidi, Mujalli Mhailan |
author_sort | Muheilan, Muheilan Mustafa |
collection | PubMed |
description | INTRODUCTION: Leydig cell tumor constitutes only about 1–3% of testicular neoplasms. There is apparently increased incidence in the last few years; one possible explanation for this phenomenon is the widespread use of ultrasound technology and the subsequent increased early detection of smaller lesions that have not been found in historical series. CASE PRESENTATION: We report a case of Leydig cell tumor of testis in a patient presenting with painless long standing slowly growing left scrotal mass who found to have intrapulmonary nodule and multiple enlarged retroperitoneal lymph nodes on staging work up. The mass was managed by radical orchiectomy. Pathological diagnosis was Leydig cell tumor. DISCUSSION: Orchiectomy is the accepted mode of treatment but follow-up every 3–6 months with physical examination, hormone assays, scrotal and abdominal ultrasonography, chest radiography, and CT scans is essential in such a case with a potential for malignant behavior. CONCLUSION: Inguinal orchiectomy is the therapeutic decision of choice and long-term follow-up is necessary to exclude recurrence or metastasis. Cases which fall in the grey zone like ours need to be followed up carefully for metastasis instead of rushing into an early retroperitoneal lymph node dissection, with its potential risks and complications. |
format | Online Article Text |
id | pubmed-5394201 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-53942012017-04-25 Leydig cell tumor in grey zone: A case report Muheilan, Muheilan Mustafa Shomaf, Maha Tarawneh, Emad Murshidi, Muayyad Mujalli Al-Sayyed, Manar Rizik Murshidi, Mujalli Mhailan Int J Surg Case Rep Case Report INTRODUCTION: Leydig cell tumor constitutes only about 1–3% of testicular neoplasms. There is apparently increased incidence in the last few years; one possible explanation for this phenomenon is the widespread use of ultrasound technology and the subsequent increased early detection of smaller lesions that have not been found in historical series. CASE PRESENTATION: We report a case of Leydig cell tumor of testis in a patient presenting with painless long standing slowly growing left scrotal mass who found to have intrapulmonary nodule and multiple enlarged retroperitoneal lymph nodes on staging work up. The mass was managed by radical orchiectomy. Pathological diagnosis was Leydig cell tumor. DISCUSSION: Orchiectomy is the accepted mode of treatment but follow-up every 3–6 months with physical examination, hormone assays, scrotal and abdominal ultrasonography, chest radiography, and CT scans is essential in such a case with a potential for malignant behavior. CONCLUSION: Inguinal orchiectomy is the therapeutic decision of choice and long-term follow-up is necessary to exclude recurrence or metastasis. Cases which fall in the grey zone like ours need to be followed up carefully for metastasis instead of rushing into an early retroperitoneal lymph node dissection, with its potential risks and complications. Elsevier 2017-04-04 /pmc/articles/PMC5394201/ /pubmed/28419904 http://dx.doi.org/10.1016/j.ijscr.2017.03.043 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Muheilan, Muheilan Mustafa Shomaf, Maha Tarawneh, Emad Murshidi, Muayyad Mujalli Al-Sayyed, Manar Rizik Murshidi, Mujalli Mhailan Leydig cell tumor in grey zone: A case report |
title | Leydig cell tumor in grey zone: A case report |
title_full | Leydig cell tumor in grey zone: A case report |
title_fullStr | Leydig cell tumor in grey zone: A case report |
title_full_unstemmed | Leydig cell tumor in grey zone: A case report |
title_short | Leydig cell tumor in grey zone: A case report |
title_sort | leydig cell tumor in grey zone: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394201/ https://www.ncbi.nlm.nih.gov/pubmed/28419904 http://dx.doi.org/10.1016/j.ijscr.2017.03.043 |
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