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Computational identification of mutually exclusive transcriptional drivers dysregulating metastatic microRNAs in prostate cancer
Androgen-ablation therapies, which are the standard treatment for metastatic prostate cancer, invariably lead to acquired resistance. Hence, a systematic identification of additional drivers may provide useful insights into the development of effective therapies. Numerous microRNAs that are critical...
Autores principales: | Xue, Mengzhu, Liu, Haiyue, Zhang, Liwen, Chang, Hongyuan, Liu, Yuwei, Du, Shaowei, Yang, Yingqun, Wang, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394245/ https://www.ncbi.nlm.nih.gov/pubmed/28397780 http://dx.doi.org/10.1038/ncomms14917 |
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