Cognate antigen engagement on parenchymal cells stimulates CD8(+) T cell proliferation in situ

T-cell responses are initiated upon cognate presentation by professional antigen presenting cells in lymphoid tissue. T cells then migrate to inflamed tissues, but further T-cell stimulation in these parenchymal target sites is not well understood. Here we show that T-cell expansion within inflamed...

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Detalles Bibliográficos
Autores principales: Sutherland, Robyn M., Londrigan, Sarah L., Brady, Jamie L., Carrington, Emma M., Marchingo, Julia M., Heinzel, Susanne, Hodgkin, Philip D., Graham, Kate L., Kay, Thomas W., Zhan, Yifan, Lew, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394288/
https://www.ncbi.nlm.nih.gov/pubmed/28401883
http://dx.doi.org/10.1038/ncomms14809

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