The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses

Mucopolysaccharidoses (MPSs) are a group of rare, genetic lysosomal storage disorders. They are caused by deficiencies of the lysosomal enzymes involved in the degradation of glycosaminoglycans (GAGs). Pain is a common feature in mucopolysaccharidoses. However, the pathophysiology of pain in this gr...

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Detalles Bibliográficos
Autores principales: Congedi, Sabrina, Di Pede, Chiara, Scarpa, Maurizio, Rampazzo, Angelica, Benini, Franca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394408/
https://www.ncbi.nlm.nih.gov/pubmed/28473938
http://dx.doi.org/10.1155/2017/7257230
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author Congedi, Sabrina
Di Pede, Chiara
Scarpa, Maurizio
Rampazzo, Angelica
Benini, Franca
author_facet Congedi, Sabrina
Di Pede, Chiara
Scarpa, Maurizio
Rampazzo, Angelica
Benini, Franca
author_sort Congedi, Sabrina
collection PubMed
description Mucopolysaccharidoses (MPSs) are a group of rare, genetic lysosomal storage disorders. They are caused by deficiencies of the lysosomal enzymes involved in the degradation of glycosaminoglycans (GAGs). Pain is a common feature in mucopolysaccharidoses. However, the pathophysiology of pain in this group of diseases is still unclear and genesis of pain is multifactorial. Currently, poor data about pain management in these patients are available. Here, we present our clinical experience in complex pain management in three children with MPS.
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spelling pubmed-53944082017-05-04 The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses Congedi, Sabrina Di Pede, Chiara Scarpa, Maurizio Rampazzo, Angelica Benini, Franca Case Rep Pediatr Case Report Mucopolysaccharidoses (MPSs) are a group of rare, genetic lysosomal storage disorders. They are caused by deficiencies of the lysosomal enzymes involved in the degradation of glycosaminoglycans (GAGs). Pain is a common feature in mucopolysaccharidoses. However, the pathophysiology of pain in this group of diseases is still unclear and genesis of pain is multifactorial. Currently, poor data about pain management in these patients are available. Here, we present our clinical experience in complex pain management in three children with MPS. Hindawi 2017 2017-04-03 /pmc/articles/PMC5394408/ /pubmed/28473938 http://dx.doi.org/10.1155/2017/7257230 Text en Copyright © 2017 Sabrina Congedi et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Congedi, Sabrina
Di Pede, Chiara
Scarpa, Maurizio
Rampazzo, Angelica
Benini, Franca
The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
title The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
title_full The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
title_fullStr The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
title_full_unstemmed The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
title_short The Complexity of Pain Management in Children Affected by Mucopolysaccharidoses
title_sort complexity of pain management in children affected by mucopolysaccharidoses
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394408/
https://www.ncbi.nlm.nih.gov/pubmed/28473938
http://dx.doi.org/10.1155/2017/7257230
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