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Establishment and characterization of an orthotopic patient-derived Group 3 medulloblastoma model for preclinical drug evaluation

Medulloblastomas comprise a heterogeneous group of tumours and can be subdivided into four molecular subgroups (WNT, SHH, Group 3 and Group 4) with distinct prognosis, biological behaviour and implications for targeted therapies. Few experimental models exist of the aggressive and poorly characteriz...

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Detalles Bibliográficos
Autores principales:	Sandén, Emma, Dyberg, Cecilia, Krona, Cecilia, Gallo-Oller, Gabriel, Olsen, Thale Kristin, Enríquez Pérez, Julio, Wickström, Malin, Estekizadeh, Atosa, Kool, Marcel, Visse, Edward, Ekström, Tomas J., Siesjö, Peter, Inge Johnsen, John, Darabi, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394470/ https://www.ncbi.nlm.nih.gov/pubmed/28417956 http://dx.doi.org/10.1038/srep46366

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