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Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

BACKGROUND: Studies assessing immune parameters typically utilize human PBMCs or murine splenocytes to generate data that is interpreted as representative of immune status. Using splenocytes, we have shown memory CD4-T cells that expand following systemic immunostimulatory therapies undergo rapid IF...

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Detalles Bibliográficos
Autores principales: Sckisel, Gail D., Mirsoian, Annie, Minnar, Christine M., Crittenden, Marka, Curti, Brendan, Chen, Jane Q., Blazar, Bruce R., Borowsky, Alexander D., Monjazeb, Arta M., Murphy, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394626/
https://www.ncbi.nlm.nih.gov/pubmed/28428882
http://dx.doi.org/10.1186/s40425-017-0235-4