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Laparoscopic surgery for complex and recurrent Crohn’s disease

Crohn’s disease (CD) is a chronic inflammatory disease of digestive tract. Approximately 70% of patients with CD require surgical intervention within 10 years of their initial diagnosis, despite advanced medical treatment alternatives including biologics, immune suppressive drugs and steroids. Refra...

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Autores principales: Sevim, Yusuf, Akyol, Cihangir, Aytac, Erman, Baca, Bilgi, Bulut, Orhan, Remzi, Feza H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394720/
https://www.ncbi.nlm.nih.gov/pubmed/28465780
http://dx.doi.org/10.4253/wjge.v9.i4.149
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author Sevim, Yusuf
Akyol, Cihangir
Aytac, Erman
Baca, Bilgi
Bulut, Orhan
Remzi, Feza H
author_facet Sevim, Yusuf
Akyol, Cihangir
Aytac, Erman
Baca, Bilgi
Bulut, Orhan
Remzi, Feza H
author_sort Sevim, Yusuf
collection PubMed
description Crohn’s disease (CD) is a chronic inflammatory disease of digestive tract. Approximately 70% of patients with CD require surgical intervention within 10 years of their initial diagnosis, despite advanced medical treatment alternatives including biologics, immune suppressive drugs and steroids. Refractory to medical treatment in CD patients is the common indication for surgery. Unfortunately, surgery cannot cure the disease. Minimally invasive treatment modalities can be suitable for CD patients due to the benign nature of the disease especially at the time of index surgery. However, laparoscopic management in fistulizing or recurrent disease is controversial. Intractable fibrotic strictures with obstruction, fistulas with abscess formation and hemorrhage are the surgical indications of recurrent CD, which are also complicating laparoscopic treatments. Nevertheless, laparoscopy can be performed in selected CD patients with safety, and may provide better outcomes compared to open surgery. The common complication after laparoscopic intervention is postoperative ileus seems and this may strongly relate excessive manipulation of the bowel during dissection. But additionally, unsuccessful laparoscopic attempts requiring conversion to open surgery have been a major concern due to presumed risk of worse outcomes. However, recent data show that conversions do not to worsen the outcomes of colorectal surgery in experienced hands. In conclusion, laparoscopic treatment modalities in recurrent CD patients have promising outcomes when it is used selectively.
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spelling pubmed-53947202017-05-02 Laparoscopic surgery for complex and recurrent Crohn’s disease Sevim, Yusuf Akyol, Cihangir Aytac, Erman Baca, Bilgi Bulut, Orhan Remzi, Feza H World J Gastrointest Endosc Editorial Crohn’s disease (CD) is a chronic inflammatory disease of digestive tract. Approximately 70% of patients with CD require surgical intervention within 10 years of their initial diagnosis, despite advanced medical treatment alternatives including biologics, immune suppressive drugs and steroids. Refractory to medical treatment in CD patients is the common indication for surgery. Unfortunately, surgery cannot cure the disease. Minimally invasive treatment modalities can be suitable for CD patients due to the benign nature of the disease especially at the time of index surgery. However, laparoscopic management in fistulizing or recurrent disease is controversial. Intractable fibrotic strictures with obstruction, fistulas with abscess formation and hemorrhage are the surgical indications of recurrent CD, which are also complicating laparoscopic treatments. Nevertheless, laparoscopy can be performed in selected CD patients with safety, and may provide better outcomes compared to open surgery. The common complication after laparoscopic intervention is postoperative ileus seems and this may strongly relate excessive manipulation of the bowel during dissection. But additionally, unsuccessful laparoscopic attempts requiring conversion to open surgery have been a major concern due to presumed risk of worse outcomes. However, recent data show that conversions do not to worsen the outcomes of colorectal surgery in experienced hands. In conclusion, laparoscopic treatment modalities in recurrent CD patients have promising outcomes when it is used selectively. Baishideng Publishing Group Inc 2017-04-16 2017-04-16 /pmc/articles/PMC5394720/ /pubmed/28465780 http://dx.doi.org/10.4253/wjge.v9.i4.149 Text en ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Editorial
Sevim, Yusuf
Akyol, Cihangir
Aytac, Erman
Baca, Bilgi
Bulut, Orhan
Remzi, Feza H
Laparoscopic surgery for complex and recurrent Crohn’s disease
title Laparoscopic surgery for complex and recurrent Crohn’s disease
title_full Laparoscopic surgery for complex and recurrent Crohn’s disease
title_fullStr Laparoscopic surgery for complex and recurrent Crohn’s disease
title_full_unstemmed Laparoscopic surgery for complex and recurrent Crohn’s disease
title_short Laparoscopic surgery for complex and recurrent Crohn’s disease
title_sort laparoscopic surgery for complex and recurrent crohn’s disease
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394720/
https://www.ncbi.nlm.nih.gov/pubmed/28465780
http://dx.doi.org/10.4253/wjge.v9.i4.149
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