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Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia

Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arter...

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Detalles Bibliográficos
Autores principales: Shukla, A, Aggarwal, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394819/
https://www.ncbi.nlm.nih.gov/pubmed/27853042
http://dx.doi.org/10.4103/0022-3859.194207
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author Shukla, A
Aggarwal, A
author_facet Shukla, A
Aggarwal, A
author_sort Shukla, A
collection PubMed
description Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arteries with no involvement of the abdomen visceral arteries. Based on significant weight loss, diastolic blood pressure >90 mmHg, myalgia, testicular pain, and angiographic abnormalities in medium-sized arteries, he was diagnosed as having PAN. He was treated with corticosteroid and bolus intravenous cyclophosphamide following which he had prompt and near-complete recovery of the symptoms without any tissue loss.
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spelling pubmed-53948192017-05-09 Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia Shukla, A Aggarwal, A J Postgrad Med Case Report Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arteries with no involvement of the abdomen visceral arteries. Based on significant weight loss, diastolic blood pressure >90 mmHg, myalgia, testicular pain, and angiographic abnormalities in medium-sized arteries, he was diagnosed as having PAN. He was treated with corticosteroid and bolus intravenous cyclophosphamide following which he had prompt and near-complete recovery of the symptoms without any tissue loss. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5394819/ /pubmed/27853042 http://dx.doi.org/10.4103/0022-3859.194207 Text en Copyright: © 2017 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Shukla, A
Aggarwal, A
Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
title Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
title_full Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
title_fullStr Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
title_full_unstemmed Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
title_short Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
title_sort polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394819/
https://www.ncbi.nlm.nih.gov/pubmed/27853042
http://dx.doi.org/10.4103/0022-3859.194207
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