Cargando…
Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia
Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arter...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394819/ https://www.ncbi.nlm.nih.gov/pubmed/27853042 http://dx.doi.org/10.4103/0022-3859.194207 |
_version_ | 1783229778956910592 |
---|---|
author | Shukla, A Aggarwal, A |
author_facet | Shukla, A Aggarwal, A |
author_sort | Shukla, A |
collection | PubMed |
description | Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arteries with no involvement of the abdomen visceral arteries. Based on significant weight loss, diastolic blood pressure >90 mmHg, myalgia, testicular pain, and angiographic abnormalities in medium-sized arteries, he was diagnosed as having PAN. He was treated with corticosteroid and bolus intravenous cyclophosphamide following which he had prompt and near-complete recovery of the symptoms without any tissue loss. |
format | Online Article Text |
id | pubmed-5394819 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-53948192017-05-09 Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia Shukla, A Aggarwal, A J Postgrad Med Case Report Acute limb ischemia and peripheral vascular disease (PVD) are unusual presentations of polyarteritis nodosa (PAN). Here, we present a case with PVD of both lower limbs leading to foot claudication. Digital subtraction angiography showed narrowing, irregularity, and occlusion of both lower limb arteries with no involvement of the abdomen visceral arteries. Based on significant weight loss, diastolic blood pressure >90 mmHg, myalgia, testicular pain, and angiographic abnormalities in medium-sized arteries, he was diagnosed as having PAN. He was treated with corticosteroid and bolus intravenous cyclophosphamide following which he had prompt and near-complete recovery of the symptoms without any tissue loss. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5394819/ /pubmed/27853042 http://dx.doi.org/10.4103/0022-3859.194207 Text en Copyright: © 2017 Journal of Postgraduate Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Shukla, A Aggarwal, A Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
title | Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
title_full | Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
title_fullStr | Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
title_full_unstemmed | Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
title_short | Polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
title_sort | polyarteritis nodosa presenting as peripheral vascular disease and acute limb ischemia |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394819/ https://www.ncbi.nlm.nih.gov/pubmed/27853042 http://dx.doi.org/10.4103/0022-3859.194207 |
work_keys_str_mv | AT shuklaa polyarteritisnodosapresentingasperipheralvasculardiseaseandacutelimbischemia AT aggarwala polyarteritisnodosapresentingasperipheralvasculardiseaseandacutelimbischemia |