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Effects of egg-adaptation on receptor-binding and antigenic properties of recent influenza A (H3N2) vaccine viruses

Influenza A virus (subtype H3N2) causes seasonal human influenza and is included as a component of influenza vaccines. The majority of vaccine viruses are isolated and propagated in eggs, which commonly results in amino acid substitutions in the haemagglutinin (HA) glycoprotein. These substitutions...

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Detalles Bibliográficos
Autores principales:	Parker, Lauren, Wharton, Stephen A., Martin, Stephen R., Cross, Karen, Lin, Yipu, Liu, Yan, Feizi, Ten, Daniels, Rodney S., McCauley, John W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2016
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394856/ https://www.ncbi.nlm.nih.gov/pubmed/26974849 http://dx.doi.org/10.1099/jgv.0.000457

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