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Population pharmacokinetics of intravenous Erwinia asparaginase in pediatric acute lymphoblastic leukemia patients

Erwinia asparaginase is an important component in the treatment of pediatric acute lymphoblastic leukemia. A large variability in serum concentrations has been observed after intravenous Erwinia asparaginase. Currently, Dutch Childhood Oncology Group protocols dose alterations are based on trough co...

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Detalles Bibliográficos
Autores principales: Sassen, Sebastiaan D.T., Mathôt, Ron A.A., Pieters, Rob, Kloos, Robin Q.H., de Haas, Valérie, Kaspers, Gertjan J.L., van den Bos, Cor, Tissing, Wim J.E., te Loo, Maroeska, Bierings, Marc B., Kollen, Wouter J.W., Zwaan, Christian M., van der Sluis, Inge M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394946/
https://www.ncbi.nlm.nih.gov/pubmed/28250007
http://dx.doi.org/10.3324/haematol.2016.149195