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Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations
A high proportion of patients with lower-risk del(5q) myelodysplastic syndromes will respond to treatment with lenalidomide. The median duration of transfusion-independence is 2 years with some long-lasting responses, but almost 40% of patients progress to acute leukemia by 5 years after starting tr...
Autores principales: | Scharenberg, Christian, Giai, Valentina, Pellagatti, Andrea, Saft, Leonie, Dimitriou, Marios, Jansson, Monika, Jädersten, Martin, Grandien, Alf, Douagi, Iyadh, Neuberg, Donna S., LeBlanc, Katarina, Boultwood, Jacqueline, Karimi, Mohsen, Jacobsen, Sten Eirik W., Woll, Petter S., Hellström-Lindberg, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394951/ https://www.ncbi.nlm.nih.gov/pubmed/27884971 http://dx.doi.org/10.3324/haematol.2016.152025 |
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