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IFNα-mediated remodeling of endothelial cells in the bone marrow niche
In the bone marrow, endothelial cells are a major component of the hematopoietic stem cell vascular niche and are a first line of defense against inflammatory stress and infection. The primary response of an organism to infection involves the synthesis of immune-modulatory cytokines, including inter...
Autores principales: | Prendergast, Áine M., Kuck, Andrea, van Essen, Mieke, Haas, Simon, Blaszkiewicz, Sandra, Essers, Marieke A. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394972/ https://www.ncbi.nlm.nih.gov/pubmed/27742772 http://dx.doi.org/10.3324/haematol.2016.151209 |
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