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The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth

Recent studies revealed C-type natriuretic peptide (CNP) and its receptor, guanylyl cyclase-B (GC-B) are potent stimulators of endochondral bone growth. As they exist ubiquitously in body, we investigated the physiological role of the local CNP/GC-B in the growth plate on bone growth using cartilage...

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Detalles Bibliográficos
Autores principales: Nakao, Kazumasa, Osawa, Kenji, Yasoda, Akihiro, Yamanaka, Shigeki, Fujii, Toshihito, Kondo, Eri, Koyama, Noriaki, Kanamoto, Naotetsu, Miura, Masako, Kuwahara, Koichiro, Akiyama, Haruhiko, Bessho, Kazuhisa, Nakao, Kazuwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395013/
https://www.ncbi.nlm.nih.gov/pubmed/26014585
http://dx.doi.org/10.1038/srep10554