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The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth
Recent studies revealed C-type natriuretic peptide (CNP) and its receptor, guanylyl cyclase-B (GC-B) are potent stimulators of endochondral bone growth. As they exist ubiquitously in body, we investigated the physiological role of the local CNP/GC-B in the growth plate on bone growth using cartilage...
Autores principales: | Nakao, Kazumasa, Osawa, Kenji, Yasoda, Akihiro, Yamanaka, Shigeki, Fujii, Toshihito, Kondo, Eri, Koyama, Noriaki, Kanamoto, Naotetsu, Miura, Masako, Kuwahara, Koichiro, Akiyama, Haruhiko, Bessho, Kazuhisa, Nakao, Kazuwa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395013/ https://www.ncbi.nlm.nih.gov/pubmed/26014585 http://dx.doi.org/10.1038/srep10554 |
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