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The molecular features of uncoupling protein 1 support a conventional mitochondrial carrier-like mechanism
Uncoupling protein 1 (UCP1) is an integral membrane protein found in the mitochondrial inner membrane of brown adipose tissue, and facilitates the process of non-shivering thermogenesis in mammals. Its activation by fatty acids, which overcomes its inhibition by purine nucleotides, leads to an incre...
Autores principales: | Crichton, Paul G., Lee, Yang, Kunji, Edmund R.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395090/ https://www.ncbi.nlm.nih.gov/pubmed/28057583 http://dx.doi.org/10.1016/j.biochi.2016.12.016 |
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