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The magnitude of ivacaftor effects on fluid secretion via R117H-CFTR channels: Human in vivo measurements
We optically measured effects of orally available ivacaftor (Kalydeco®) on sweat rates of identified glands in 3 R117H subjects, each having a unique set of additional mutations, and compared them with 5 healthy control subjects tested contemporaneously. We injected β-adrenergic agonists intradermal...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395152/ https://www.ncbi.nlm.nih.gov/pubmed/28419121 http://dx.doi.org/10.1371/journal.pone.0175486 |