Cargando…
Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis
Mycobacterium smegmatis represents one model for studying the biology of its pathogenic relative Mycobacterium tuberculosis. The structural characterization of a M. tuberculosis ortholog protein can serve as a valid tool for the development of molecules active against the M. tuberculosis target. In...
Autores principales: | Donini, Stefano, Garavaglia, Silvia, Ferraris, Davide M., Miggiano, Riccardo, Mori, Shigetarou, Shibayama, Keigo, Rizzi, Menico |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395218/ https://www.ncbi.nlm.nih.gov/pubmed/28419153 http://dx.doi.org/10.1371/journal.pone.0175815 |
Ejemplares similares
-
Mycobacterium tuberculosis Phosphoribosylpyrophosphate Synthetase: Biochemical Features of a Crucial Enzyme for Mycobacterial Cell Wall Biosynthesis
por: Lucarelli, Anna P., et al.
Publicado: (2010) -
Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis
por: Donini, Stefano, et al.
Publicado: (2017) -
Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment
por: Miggiano, Riccardo, et al.
Publicado: (2020) -
Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets
por: Ferraris, Davide M., et al.
Publicado: (2018) -
Biochemical Characterization of Quinolinic Acid Phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv and Inhibition of Its Activity by Pyrazinamide
por: Kim, Hyun, et al.
Publicado: (2014)