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Spectrophotometric and molecular modelling studies on in vitro interaction of tyrosine kinase inhibitor linifanib with bovine serum albumin

Linifanib (LNF) possess antitumor activity and acts by inhibiting receptor tyrosine kinase VEGF and PDGF. The interaction of BSA with the drug can provide valuable information regarding the pharmacokinetic and pharmacodynamics behavior of drug. In our study the spectrophotometric methods and molecul...

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Detalles Bibliográficos
Autores principales:	Wani, Tanveer A., Bakheit, Ahmed H., Zargar, Seema, Hamidaddin, Mohammed A., Darwish, Ibrahim A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395234/ https://www.ncbi.nlm.nih.gov/pubmed/28419132 http://dx.doi.org/10.1371/journal.pone.0176015

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