Cargando…

Bioequivalence study of a new sildenafil 100 mg orodispersible film compared to the conventional film-coated 100 mg tablet administered to healthy male volunteers

A new orodispersible film formulation of the phosphodiesterase type 5 inhibitor, sildenafil, has been developed to examine the advantages of an orally disintegrating film formulation and provide an alternative to the current marketed products for the treatment of erectile dysfunction. The pharmacoki...

Descripción completa

Detalles Bibliográficos
Autores principales:	Radicioni, Milko, Castiglioni, Chiara, Giori, Andrea, Cupone, Irma, Frangione, Valeria, Rovati, Stefano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395281/ https://www.ncbi.nlm.nih.gov/pubmed/28442892 http://dx.doi.org/10.2147/DDDT.S124034

Ejemplares similares

Pharmacokinetics of a Novel Sildenafil Orodispersible Film Administered by the Supralingual and the Sublingual Route to Healthy Men
por: Loprete, Luca, et al.
Publicado: (2018)

Comparative Bioavailability Study of a New Vitamin D3 Orodispersible Film Versus a Marketed Oral Solution in Healthy Volunteers
por: Radicioni, Milko, et al.
Publicado: (2022)

Bioequivalence Studies of Sildenafil Citrate Orodispersible Film Administered with and without Water vs Viagra(Ⓡ) Film-Coated Tablets in Healthy Male Volunteers
por: Shaw, Andrew, et al.
Publicado: (2023)

Development and Characterization of an Orodispersible Film for Vitamin D3 Supplementation
por: Cupone, Irma Elisa, et al.
Publicado: (2020)

Orodispersible Film (ODF) Platform Based on Maltodextrin for Therapeutical Applications
por: Cupone, Irma E., et al.
Publicado: (2022)

Effect of the new 75-mg orodispersible film of sildenafil on erection and sexual quality of life: insights from an observational study
por: Sansone, Andrea, et al.
Publicado: (2023)

Bioequivalence Study of 100-mg Cilostazol Tablets in Healthy Thai Adult Volunteers
por: Chatsiricharoenkul, Somruedee, et al.
Publicado: (2019)

Bioequivalence and Bioavailability of an Orodispersible Tablet of Sildenafil Citrate in Healthy Chinese Male Subjects
por: Lv, Yuan, et al.
Publicado: (2020)

Orodispersible Film Based on Maltodextrin: A Convenient and Suitable Method for Iron Supplementation
por: Cupone, Irma Elisa, et al.
Publicado: (2023)

Pharmacokinetics and Safety of a Diclofenac Sodium 75 mg/1 mL Solution (Akis(®)/Dicloin(®)) Administered as a Single Intravenous Bolus Injection in Healthy Men and Women
por: Leuratti, Chiara, et al.
Publicado: (2019)

Bioequivalence Study of Two Orodispersible Rizatriptan Formulations of 10 mg in Healthy Volunteers
por: Cánovas, Mercè, et al.
Publicado: (2016)

Relative Bioavailability and Bioequivalence of Brivaracetam 10 mg/mL Oral Solution and 50‐mg Film‐Coated Tablet
por: Otoul, Christian, et al.
Publicado: (2016)

Pharmacokinetics and bioequivalence assessment of optimized directly compressible Aceclofenac (100 mg) tablet formulation in healthy human subjects
por: Bushra, Rabia, et al.
Publicado: (2020)

Improvement in erection hardness and intercourse success with first dose of sildenafil citrate 100 mg
por: Mulhall, John P, et al.
Publicado: (2013)

Heteroepitaxial growth of TiN film on MgO (100) by reactive magnetron sputtering
por: Chen, Wei-Chun, et al.
Publicado: (2014)

Bioequivalence of the 4-mg Oral Granules and Chewable Tablet Formulations of Montelukast
por: Knorr, Barbara, et al.
Publicado: (2010)

Comparative bioequivalence studies of tramadol hydrochloride sustained-release 200 mg tablets
por: Khandave, Suhas S, et al.
Publicado: (2010)

Magnetic and transport properties of epitaxial thin film MgFe(2)O(4) grown on MgO (100) by molecular beam epitaxy
por: Wu, Han-Chun, et al.
Publicado: (2014)

Comparison of tadalafil pharmacokinetics after administration of a new orodispersible film versus a film-coated tablet
por: Park, Sang-In, et al.
Publicado: (2018)

A comparison of preference for and efficacy of tablet formulations of sumatriptan (50 mg and 100 mg), naratriptan (2.5 mg), rizatriptan (10 mg), and zolmitriptan (2.5 mg) in the acute treatment of migraine
por: Dahlöf, Carl, et al.
Publicado: (2004)

Bioavailability Evaluation of Venetoclax Lower-Strength Tablets and Oral Powder Formulations to Establish Interchangeability with the 100 mg Tablet
por: Badawi, Mohamed, et al.
Publicado: (2022)

Effect of combination tablets containing amlodipine 10 mg and irbesartan 100 mg on blood pressure and cardiovascular risk factors in patients with hypertension
por: Yagi, Shusuke, et al.
Publicado: (2015)

Bioequivalence of generic alendronate sodium tablets (70 mg) to Fosamax(®) tablets (70 mg) in fasting, healthy volunteers: a randomized, open-label, three-way, reference-replicated crossover study
por: Zhang, Yifan, et al.
Publicado: (2017)

Bioequivalence Comparison of Two Formulations of Fixed-Dose Combination Glimepiride/Metformin (2/500 mg)Tablets in Healthy Volunteers
por: Jung, Sang-hoon, et al.
Publicado: (2014)

Pharmacokinetics and Bioequivalence of Two Formulations of Febuxostat 40-Mg and 80-Mg Tablets: A Randomized, Open-Label, 4-Way Crossover Study in Healthy Chinese Male Volunteers
por: Luo, Zhu, et al.
Publicado: (2016)

Bioequivalence Study Of A Fixed-Dose Combination Tablet Containing Melitracen 10 mg And Flupentixol 0.5 mg In Healthy Chinese Volunteers Under Fasted And Fed Conditions
por: Wu, Lihua, et al.
Publicado: (2019)

Bioequivalence of a biosimilar enoxaparin sodium to Clexane(®) after single 100 mg subcutaneous dose: results of a randomized, double-blind, crossover study in healthy volunteers
por: Martínez González, Javier, et al.
Publicado: (2018)

Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of Pediatric Pulmonary Hypertension Using Response Surface Methodology
por: Alalaiwe, Ahmed, et al.
Publicado: (2023)

Comparison of pharmacokinetic characteristics of sildenafil citrate chewable tablets and film-coated tablets in healthy male subjects
por: Yoo, Hyounggyoon, et al.
Publicado: (2017)

Bioequivalence Study of Two Formulations of Ibandronic Acid 150-mg Film-Coated Tablets in Healthy Volunteers Under Fasting Conditions: A Randomized, Open-Label, Three-Way, Reference-Replicated Crossover Study
por: Filipe, Augusto, et al.
Publicado: (2014)

The Bioequivalence of Tafamidis 61‐mg Free Acid Capsules and Tafamidis Meglumine 4 × 20‐mg Capsules in Healthy Volunteers
por: Lockwood, Peter A., et al.
Publicado: (2020)

Electrospun Orodispersible Films of Isoniazid for Pediatric Tuberculosis Treatment
por: Chachlioutaki, Konstantina, et al.
Publicado: (2020)

Development of an Orodispersible Film Containing Stabilized Influenza Vaccine
por: Tian, Yu, et al.
Publicado: (2020)

Concept of Orodispersible or Mucoadhesive “Tandem Films” and Their Pharmaceutical Realization
por: Göbel, Anja, et al.
Publicado: (2022)

Development and Characterization of Pullulan-Based Orodispersible Films of Iron
por: Gupta, Maram Suresh, et al.
Publicado: (2023)

Bioequivalence study of two formulations of bisoprolol fumarate film-coated tablets in healthy subjects
por: Tjandrawinata, Raymond R, et al.
Publicado: (2012)

Bioavailability of everolimus administered as a single 5 mg tablet versus five 1 mg tablets: a randomized, open-label, two-way crossover study of healthy volunteers
por: Thudium, Karen, et al.
Publicado: (2015)

Formulation and characterization of orodispersible tablet of glimepiride
por: Kinani, Ahmad AB Yosef, et al.
Publicado: (2022)

$^{57}$Fe Mössbauer study of epitaxial TiN thin film grown on MgO (1 0 0) by magnetron sputtering
por: Qi, B, et al.
Publicado: (2019)

The Pharmacokinetics and Relative Bioavailability of Mepolizumab 100 mg Liquid Formulation Administered Subcutaneously to Healthy Participants: A Randomized Trial
por: Shabbir, Shaila, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n0me9gvqou1tkee5lli16fvlaj