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Design, synthesis, and biological evaluation of the novel glycyrrhetinic acid-cinnamoyl hybrids as anti-tumor agents

BACKGROUND: Glycyrrhetinic acid (GA) derivatives had shown not only cytotoxicity but also could trigger apoptosis in various human cancer cell lines. Moreover, cinnamic acid (CA) and its phenolic analogues as potent antitumor agents were employed in the design of anti-tumor drugs. To further improve...

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Detalles Bibliográficos
Autores principales:	Guo, Wenbo, Yan, Mengmeng, Xu, Bing, Chu, Fuhao, Wang, Wei, Zhang, Chenze, Jia, Xiaohui, Han, Yaotian, Xiang, Hongjun, Zhang, Yuzhong, Wang, Penglong, Lei, Haimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5395518/ http://dx.doi.org/10.1186/s13065-016-0222-8

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